以濾紙為模板合成新型介孔生物活性玻璃微管材料
發(fā)布時(shí)間：2018-07-31 07:10
【摘要】：用快速濾紙為生物模板,通過(guò)先浸漬后焙燒的方法合成了介孔生物活性玻璃微管材料�？焖贋V紙的管狀結(jié)構(gòu)被完美復(fù)制,其管壁為生成的介孔生物玻璃材料。通過(guò)在合成過(guò)程中引入鐵元素可以使材料具有一定的磁性。材料的形貌、結(jié)構(gòu)和磁性通過(guò)掃描電鏡、粉末X射線衍射、透射電鏡、氮?dú)馕?脫附曲線,紅外光譜和磁滯回線進(jìn)行了表征。并且通過(guò)模擬體液浸泡方法考察了其礦化能力,以地塞米松為模型藥物考察其釋藥能力和生物相容性。合成的介孔生物活性玻璃微管材料具有復(fù)雜的管狀多級(jí)結(jié)構(gòu)、快速的礦化能力和良好的生物相容性,并具備一定的磁性,是一種不可多得的藥物緩釋材料。
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者單位】： 吉林大學(xué)食品科學(xué)與工程學(xué)院;
【基金】：國(guó)家自然科學(xué)基金(No.31402251) 教育部高等學(xué)校博士學(xué)科點(diǎn)專(zhuān)項(xiàng)科研基金(No.20130061120116)資助項(xiàng)目
【分類(lèi)號(hào)】：TB383.4;TQ460.1
本文編號(hào)：2154822
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者單位】： 吉林大學(xué)食品科學(xué)與工程學(xué)院;
【基金】：國(guó)家自然科學(xué)基金(No.31402251) 教育部高等學(xué)校博士學(xué)科點(diǎn)專(zhuān)項(xiàng)科研基金(No.20130061120116)資助項(xiàng)目
【分類(lèi)號(hào)】：TB383.4;TQ460.1
【相似文獻(xiàn)】
相關(guān)博士學(xué)位論文 前2條
1 苗國(guó)厚;用于藥物及基因載體研究的介孔生物活性玻璃的制備及其性能研究[D];華南理工大學(xué);2014年
2 胡慶;用于牙髓損傷修復(fù)的新型微納米生物活性玻璃的仿生制備及性能研究[D];華南理工大學(xué);2014年
相關(guān)碩士學(xué)位論文 前5條
1 梁隔;單分散磁性介孔生物活性玻璃微球及其高分子復(fù)合微球的制備和應(yīng)用研究[D];揚(yáng)州大學(xué);2016年
2 馬杰;功能化多級(jí)孔生物活性玻璃的合成及成骨與藥物緩釋性能研究[D];哈爾濱師范大學(xué);2014年
3 劉惠;生物活性玻璃纖維的制備及基因轉(zhuǎn)染研究[D];華南理工大學(xué);2014年
4 連鵬飛;生物活性玻璃/碳復(fù)合納米纖維的制備及其生物性能研究[D];北京化工大學(xué);2010年
5 司云鳳;單分散磁性介孔生物活性玻璃/聚乙二醇（MMBGs/PEG）復(fù)合微球的制備及應(yīng)用研究[D];揚(yáng)州大學(xué);2013年
，本文編號(hào)：2154822
本文鏈接：http://www.wukwdryxk.cn/kejilunwen/cailiaohuaxuelunwen/2154822.html
最近更新
教材專(zhuān)著
