以濾紙為模板合成新型介孔生物活性玻璃微管材料
發(fā)布時(shí)間:2018-07-31 07:10
【摘要】:用快速濾紙為生物模板,通過(guò)先浸漬后焙燒的方法合成了介孔生物活性玻璃微管材料?焖贋V紙的管狀結(jié)構(gòu)被完美復(fù)制,其管壁為生成的介孔生物玻璃材料。通過(guò)在合成過(guò)程中引入鐵元素可以使材料具有一定的磁性。材料的形貌、結(jié)構(gòu)和磁性通過(guò)掃描電鏡、粉末X射線衍射、透射電鏡、氮?dú)馕?脫附曲線,紅外光譜和磁滯回線進(jìn)行了表征。并且通過(guò)模擬體液浸泡方法考察了其礦化能力,以地塞米松為模型藥物考察其釋藥能力和生物相容性。合成的介孔生物活性玻璃微管材料具有復(fù)雜的管狀多級(jí)結(jié)構(gòu)、快速的礦化能力和良好的生物相容性,并具備一定的磁性,是一種不可多得的藥物緩釋材料。
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者單位】: 吉林大學(xué)食品科學(xué)與工程學(xué)院;
【基金】:國(guó)家自然科學(xué)基金(No.31402251) 教育部高等學(xué)校博士學(xué)科點(diǎn)專(zhuān)項(xiàng)科研基金(No.20130061120116)資助項(xiàng)目
【分類(lèi)號(hào)】:TB383.4;TQ460.1
本文編號(hào):2154822
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者單位】: 吉林大學(xué)食品科學(xué)與工程學(xué)院;
【基金】:國(guó)家自然科學(xué)基金(No.31402251) 教育部高等學(xué)校博士學(xué)科點(diǎn)專(zhuān)項(xiàng)科研基金(No.20130061120116)資助項(xiàng)目
【分類(lèi)號(hào)】:TB383.4;TQ460.1
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,本文編號(hào):2154822
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