非環(huán)狀鹵胺抗菌材料的合成及其性能研究
發(fā)布時間：2018-08-03 20:20
【摘要】：隨著生活水平的提高,人們對自身生活健康的要求也越來越高,但日常生活中,微生物污染給人們生命安全造成的威脅時有發(fā)生,因此開發(fā)新型抗菌材料來保障人們生活的衛(wèi)生和安全變得尤為重要。目前,鹵胺抗菌材料由于其強大的抗菌功效、抗菌官能團的可再生性和抗菌的廣譜性而引起研究者的廣泛興趣,但非環(huán)狀鹵胺抗菌材料的研究較少,本文合成了一種非環(huán)狀鹵胺聚合物大孔交聯(lián)抗菌樹脂,制備了一種非環(huán)狀鹵胺接枝棉纖維材料。主要研究內(nèi)容如下:(1)非環(huán)狀鹵胺聚合物大孔交聯(lián)抗菌樹脂的合成及其性能研究以甲基丙烯酰胺為單體,亞甲基雙丙烯酰胺和環(huán)氧氯丙烷為交聯(lián)劑,通過懸浮聚合合成了一種非環(huán)狀鹵胺前置體聚合物大孔交聯(lián)樹脂P(AA-MBA-EPI),再經(jīng)過在次氯酸鈉溶液中的氯化反應(yīng),得到了一種非環(huán)狀鹵胺聚合物大孔交聯(lián)樹脂P(AA-MBA-EPI-Cl)。通過場發(fā)射掃描電鏡(FE-SEM)、紅外光譜(FTIR)、Brunauer-Emmet-Teller(BET)分析、X射線能譜(XPS)對材料進行了表征。BET分析和氧化態(tài)氯含量測試表明:制備的P(AA-MBA-EPI-Cl)的比表面積可達到135.2m2/g,且氧化態(tài)氯含量可高達10.05%,非常適用于飲用水的快速殺菌消毒�？咕阅軠y試表明:制備的P(AA-MBA-EPI-Cl)可在1 min之內(nèi)全部殺死濃度為1×106 CFU/mL的大腸桿菌和金黃的葡萄球菌。另外,我們還對制備的P(AA-MBA-EPI-Cl)中的鹵胺抗菌官能團的再生性能和儲存穩(wěn)定性進行了初步的評價。(2)非環(huán)狀鹵胺接枝棉纖維材料的制備及其性能與研究在水相中通過一種高效的固相催化反應(yīng)使亞甲基雙丙烯酰胺(MBA)以共價鍵的形式接枝到棉纖維表面,接枝后的棉纖維(棉布-MBA)通過場發(fā)射掃描電鏡和紅外光譜分析得到了表征。經(jīng)過在稀釋的次氯酸鈉溶液中氯化后,棉布-MBA上的酰胺官能團轉(zhuǎn)化成了鹵胺官能團,即得到了耐洗性好的非環(huán)狀鹵胺抗菌棉纖維(棉布-MBA-Cl)�？咕阅軠y試表明,棉布-MBA-Cl可在1 min內(nèi)完全殺死濃度為5.78×107 CFU/m L的金黃色的葡萄球菌和濃度為7.58×108 CFU/m L的大腸桿菌。洗脫性能測試顯示,經(jīng)過50次的洗脫循環(huán)后,棉布-MBA-Cl仍然含有0.06%的氧化態(tài)氯,且經(jīng)過再次氯化后,其氧化態(tài)氯含量可達到0.30%。這表明棉布-MBA-Cl上的鹵胺官能團和棉布與MBA之間形成的共價鍵都具有良好的耐水洗性能。儲存穩(wěn)定性測試顯示,經(jīng)過三十天的儲存,棉布-MBA-Cl的氯含量從0.43%降到了0.32%,表明棉布-MBA-Cl上的鹵胺官能團在室溫下具有良好的儲存穩(wěn)定性。并且,由于對棉纖維的接枝和氯化條件都比較溫和,對棉布-MBA-Cl的拉伸強度測試表明,接枝和氯化過程對棉纖維結(jié)構(gòu)沒有造成明顯的破壞。
[Abstract]:With the improvement of living standards, people have higher and higher requirements for their own health, but in daily life, the threat of microbial pollution to people's lives occurs from time to time. Therefore, the development of new antimicrobial materials to protect people's lives of health and safety has become particularly important. At present, halogen amine antimicrobial materials have attracted extensive interest due to their strong antibacterial efficacy, antibacterial functional group reproducibility and antimicrobial broad-spectrum, but less research has been done on non-cyclic halogenamine antimicrobial materials. In this paper, a macroporous cross-linked antibacterial resin was synthesized and a non-cyclic halogen amine graft cotton fiber material was prepared. The main research contents are as follows: (1) Synthesis and properties of macroporous antibacterial resin of non-cyclic halogenamine polymer; Methyl acrylamide as monomer, methylene bisacrylamide and epichlorohydrin as crosslinker, A kind of macroporous crosslinked resin P (AA-MBA-EPI) was synthesized by suspension polymerization. After chlorination in sodium hypochlorite solution, a macroporous cross-linked resin P (AA-MBA-EPI-Cl) was obtained. Field emission scanning electron microscopy (FE-SEM), (FTIR) Brunauer-Emmet-Teller (BET) analysis and X-ray energy dispersive (XPS) were used to characterize the materials. The results showed that the specific surface area of the prepared P (AA-MBA-EPI-Cl) was 135.2 m2 / g, and the oxidized chlorine content could reach 10.05%. Very suitable for rapid disinfection of drinking water. The antimicrobial activity test showed that the prepared P (AA-MBA-EPI-Cl) could completely kill Escherichia coli and Staphylococcus aureus with a concentration of 1 脳 10 ~ 6 CFU/mL within 1 min. In addition, We also evaluated the regeneration and storage stability of halogenamine antibacterial functional groups in P (AA-MBA-EPI-Cl). (2) preparation of acyclic halogen grafted cotton fiber materials and their properties and studies in aqueous phase. The solid phase catalytic reaction made methylene bisacrylamide (MBA) grafted to the surface of cotton fiber in the form of covalent bond. The grafted cotton fiber (cotton-MBA) was characterized by field emission scanning electron microscopy and infrared spectroscopy. After chlorination in dilute sodium hypochlorite solution, the amide functional group on cotton cloth / MBA was converted into halogen functional group, and a washable non-cyclic haloamine antibacterial cotton fiber (cotton cloth MBA-Cl) was obtained. The antibacterial activity test showed that cotton cloth MBA-Cl could completely kill the Staphylococcus aureus and Escherichia coli at the concentration of 5.78 脳 10 ~ 7 CFU/m / L and 7.58 脳 10 ~ 8 CFU/m / L within 1 min. After 50 elution cycles, the cotton cloth MBA-Cl still contains 0.06% of oxidized chlorine, and after re-chlorination, the content of oxidized chlorine can reach 0.30%. The results show that the halogen functional groups on cotton cloth MBA-Cl and the covalent bonds formed between cotton cloth and MBA have good washing resistance. The storage stability test showed that the chlorine content of cotton cloth MBA-Cl decreased from 0.43% to 0.32% after 30 days storage, which indicated that the halogen functional groups on cotton cloth MBA-Cl had good storage stability at room temperature. Because of the mild grafting and chlorination conditions of cotton fiber, the tensile strength test of cotton cloth MBA-Cl shows that the grafting and chlorination process have no obvious damage to the cotton fiber structure.
【學(xué)位授予單位】：上海師范大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：TB34
本文編號：2162896
[Abstract]:With the improvement of living standards, people have higher and higher requirements for their own health, but in daily life, the threat of microbial pollution to people's lives occurs from time to time. Therefore, the development of new antimicrobial materials to protect people's lives of health and safety has become particularly important. At present, halogen amine antimicrobial materials have attracted extensive interest due to their strong antibacterial efficacy, antibacterial functional group reproducibility and antimicrobial broad-spectrum, but less research has been done on non-cyclic halogenamine antimicrobial materials. In this paper, a macroporous cross-linked antibacterial resin was synthesized and a non-cyclic halogen amine graft cotton fiber material was prepared. The main research contents are as follows: (1) Synthesis and properties of macroporous antibacterial resin of non-cyclic halogenamine polymer; Methyl acrylamide as monomer, methylene bisacrylamide and epichlorohydrin as crosslinker, A kind of macroporous crosslinked resin P (AA-MBA-EPI) was synthesized by suspension polymerization. After chlorination in sodium hypochlorite solution, a macroporous cross-linked resin P (AA-MBA-EPI-Cl) was obtained. Field emission scanning electron microscopy (FE-SEM), (FTIR) Brunauer-Emmet-Teller (BET) analysis and X-ray energy dispersive (XPS) were used to characterize the materials. The results showed that the specific surface area of the prepared P (AA-MBA-EPI-Cl) was 135.2 m2 / g, and the oxidized chlorine content could reach 10.05%. Very suitable for rapid disinfection of drinking water. The antimicrobial activity test showed that the prepared P (AA-MBA-EPI-Cl) could completely kill Escherichia coli and Staphylococcus aureus with a concentration of 1 脳 10 ~ 6 CFU/mL within 1 min. In addition, We also evaluated the regeneration and storage stability of halogenamine antibacterial functional groups in P (AA-MBA-EPI-Cl). (2) preparation of acyclic halogen grafted cotton fiber materials and their properties and studies in aqueous phase. The solid phase catalytic reaction made methylene bisacrylamide (MBA) grafted to the surface of cotton fiber in the form of covalent bond. The grafted cotton fiber (cotton-MBA) was characterized by field emission scanning electron microscopy and infrared spectroscopy. After chlorination in dilute sodium hypochlorite solution, the amide functional group on cotton cloth / MBA was converted into halogen functional group, and a washable non-cyclic haloamine antibacterial cotton fiber (cotton cloth MBA-Cl) was obtained. The antibacterial activity test showed that cotton cloth MBA-Cl could completely kill the Staphylococcus aureus and Escherichia coli at the concentration of 5.78 脳 10 ~ 7 CFU/m / L and 7.58 脳 10 ~ 8 CFU/m / L within 1 min. After 50 elution cycles, the cotton cloth MBA-Cl still contains 0.06% of oxidized chlorine, and after re-chlorination, the content of oxidized chlorine can reach 0.30%. The results show that the halogen functional groups on cotton cloth MBA-Cl and the covalent bonds formed between cotton cloth and MBA have good washing resistance. The storage stability test showed that the chlorine content of cotton cloth MBA-Cl decreased from 0.43% to 0.32% after 30 days storage, which indicated that the halogen functional groups on cotton cloth MBA-Cl had good storage stability at room temperature. Because of the mild grafting and chlorination conditions of cotton fiber, the tensile strength test of cotton cloth MBA-Cl shows that the grafting and chlorination process have no obvious damage to the cotton fiber structure.
【學(xué)位授予單位】：上海師范大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：TB34
【參考文獻】
相關(guān)期刊論文 前1條
1 姜永軍;飲用水消毒技術(shù)[J];甘肅科技;2004年05期
，本文編號：2162896
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