a国产,中文字幕久久波多野结衣AV,欧美粗大猛烈老熟妇,女人av天堂

基于ALFF的OSAHS患者腦功能變化及臨床相關(guān)研究

發(fā)布時(shí)間:2018-01-15 19:10

  本文關(guān)鍵詞:基于ALFF的OSAHS患者腦功能變化及臨床相關(guān)研究 出處:《新疆醫(yī)科大學(xué)》2017年碩士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 睡眠呼吸暫停綜合征 低頻振幅 功能磁共振成像


【摘要】:目的:探索阻塞性睡眠呼吸暫停低通氣綜合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者和正常對(duì)照組的大腦神經(jīng)元自發(fā)活動(dòng)差異及其與OSAHS嚴(yán)重程度的關(guān)系。方法:收集30例OSAHS患者及體檢健康者23例,均接受靜息態(tài)功能磁共振(resting-state functional magnetic resonance imaging,rs-fMRI)掃描及MoCA評(píng)分,患者組進(jìn)行多導(dǎo)睡眠監(jiān)測,并在磁共振掃描前24h內(nèi)進(jìn)行了上氣道CT測量,對(duì)兩組圖像數(shù)據(jù)進(jìn)行處理比較并進(jìn)行相關(guān)性分析。結(jié)果:與HC組相比,OSAHS組雙側(cè)海馬旁回、顳葉及梭狀回、右側(cè)額葉及左側(cè)小腦低頻振幅活動(dòng)明顯增強(qiáng),差異具有統(tǒng)計(jì)學(xué)意義(P0.005);雙側(cè)頂葉、兩側(cè)楔前葉及前扣帶回的低頻振幅活動(dòng)減弱,差異具有統(tǒng)計(jì)學(xué)意義(P0.005);經(jīng)Pearson相關(guān)性分析結(jié)果顯示,雙側(cè)海馬旁回、顳葉及梭狀回與OSAHS組ALFF呈負(fù)相關(guān),雙側(cè)頂葉ALFF值與OSAHS患者的呼吸暫停低通氣指數(shù)(apnea-hypopnea index,AHI)呈顯著負(fù)相關(guān)(P0.005);雙側(cè)楔前葉及前扣帶回的ALFF值與MoCA評(píng)分之間呈顯著正相關(guān)(P0.005)。結(jié)論:fMRI技術(shù)能夠探測到OSAHS患者腦組織功能發(fā)生的變化,為OSAHS患者和正常對(duì)照者的鑒別與診斷提供有效的影像學(xué)方法。
[Abstract]:Objective: to explore obstructive sleep apnea-hypopnea syndrome in obstructive sleep apnea hypopnea syndrome. The relationship between the spontaneous activity of brain neurons and the severity of OSAHS in patients with OSAHS and normal controls. Methods: 30 patients with OSAHS and 23 healthy controls were collected. All patients received rest state functional magnetic resonance imaging. Rs-fMRI (rs-fMRI) scan and MoCA score, polysomnography was performed in the patient group, and the upper airway CT was measured within 24 hours before Mr scan. Results: compared with HC group, OSAHS group had bilateral parahippocampal gyrus, temporal lobe and fusiform gyrus. The low frequency amplitude activity in the right frontal lobe and left cerebellum was significantly increased (P 0.005). In bilateral parietal lobe, the low frequency amplitude activity of bilateral anterior cuneate lobe and anterior cingulate gyrus decreased, and the difference was statistically significant (P 0.005). The results of Pearson correlation analysis showed that bilateral parahippocampal gyrus, temporal lobe and fusiform gyrus were negatively correlated with ALFF in OSAHS group. Bilateral parietal lobe ALFF was negatively correlated with apnea hypopnea index (P0.005) in patients with OSAHS. There was a significant positive correlation between ALFF and MoCA score in bilateral anterior wedge and anterior cingulate gyrus (P0.005). Conclusion the brain tissue function of patients with OSAHS can be detected by the technique of FMRI. To provide an effective imaging method for the differentiation and diagnosis of OSAHS patients and normal controls.
【學(xué)位授予單位】:新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R766;R445.2

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 雷旭;趙文瑞;;睡眠影響記憶鞏固的同步EEG-fMRI研究[J];心理科學(xué)進(jìn)展;2016年03期

2 王青云;陳銳;曹忠勝;袁輝;趙婉君;李小波;鄔曉帆;辛潔;劉志勇;李文全;;同期多平面手術(shù)對(duì)中青年中-重度OSAHS患者血清氧化應(yīng)激水平和認(rèn)知功能的影響[J];臨床耳鼻咽喉頭頸外科雜志;2015年24期

3 曹豈溱;牛彩虹;齊進(jìn)沖;楊冀萍;;磁共振對(duì)阻塞性睡眠呼吸暫停低通氣綜合征腦結(jié)構(gòu)及功能評(píng)價(jià)的研究進(jìn)展[J];腦與神經(jīng)疾病雜志;2015年03期

4 尤麗麗;郭愛敏;趙艷偉;伍青;;阻塞性睡眠呼吸暫停綜合征患者認(rèn)知功能現(xiàn)狀及人口學(xué)影響因素分析[J];護(hù)理學(xué)報(bào);2015年04期

5 劉會(huì)茹;王維卓;王欣;陶潔潔;聞彩云;王漢e,

本文編號(hào):1429668


資料下載
論文發(fā)表

本文鏈接:http://www.wukwdryxk.cn/shoufeilunwen/mpalunwen/1429668.html


Copyright(c)文論論文網(wǎng)All Rights Reserved | 網(wǎng)站地圖 |

版權(quán)申明:資料由用戶fb896***提供,本站僅收錄摘要或目錄,作者需要?jiǎng)h除請(qǐng)E-mail郵箱bigeng88@qq.com
亚洲国产一区二区三区四区色欲| 中文字幕欧美人妻精品二区| 少妇午夜福利一区二区 | 冈本视频| 奇米444| 日韩第三页| 亚洲精品18| 国产精品区一区二区三含羞草 | 亚洲综合色无码| 牛牛视频一区二区三区| 99精品偷自拍| 国产成人无码Av在线播放无广告| 中文字幕一区二区精品区| 免费无码av片在线观看播放| 日韩AV无码精品一二三区| 亚洲国产婷婷香蕉久久久久久| 亚洲成aⅴ人片久青草影院| 国内精品视频一区二区三区| WWW性久久久COM| 熟妇人妻中文a∨无码| 亚洲伊人丝袜精品久久| 最近中文2019字幕第二页| 日本午夜精品理论片A级APP发布| 亚洲AV无码久久久久网站蜜桃| 久久97人人超人人超碰超国产| 松阳县| 亚洲av午夜成人片精品| 亚洲综合一区二区三区无码| 国内精品国产三级国产AV| 18禁肉肉无遮挡无码网站| 久久精品国产99国产精2021| 国产高潮流白浆喷水在线观看| 四虎成人精品永久网站 | 亚洲AV专区无码观看精品天堂 | 免费在线视频你懂的| 三年片大全在线观看免费观看大全| 亚洲影院天堂中文av色| 1000部啪啪未满十八勿入| 香蕉依人| 色综合| 欧美一区二区三区视频在线观看|