發(fā)布時間：2018-01-19 09:46

  本文關(guān)鍵詞： IgA腎病 中性細(xì)胞淋巴細(xì)胞比值(NLR) Lee分級　出處：《青海大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討Ig A腎病患者中性粒細(xì)胞淋巴細(xì)胞比值(NLR)與Ig A腎病臨床及病理特點。方法:回顧性收集于青海大學(xué)附屬醫(yī)院腎病科經(jīng)腎活檢確診為Ig A腎病的住院患者病例共56例(2012.05-2016.10),研究中性粒細(xì)胞淋巴細(xì)胞比值(NLR)與Ig A腎病臨床及病理特點。結(jié)果:56例Ig A腎病患者中,男性41例,女性15例,男女比例2.7:1。年齡為34±11歲。LeeⅠ級1例,Ⅱ級31例,Ⅲ級14例,Ⅳ級5例,Ⅴ級5例。Ig A腎病患者中,各Lee等級NLR比較有統(tǒng)計學(xué)意義(P0.05),LeeⅡ級和LeeⅣ間有差異(P0.05),LeeⅡ級和LeeⅤ級間有差異(P0.05)。NLR與Lee分級(r=0.426,P0.05)、血肌酐(r=0.415,P0.05)、尿素氮(r=0.298,P0.05)、e GFR(r=-0.324,P0.05)相關(guān)。NLR與血肌酐密切相關(guān)(P0.05)。結(jié)論:隨著Lee分級加重,NLR有升高趨勢,提示NLR可以作為判斷腎臟腎臟損害的一項指標(biāo);NLR與血肌酐密切相關(guān),提示隨著血肌酐水平逐漸增高,炎性反應(yīng)逐漸加重。
[Abstract]:Objective: to investigate the neutrophil lymphocyte ratio (NLR) in patients with IgA nephropathy. Clinical and pathological features of IgA nephropathy. Methods: a total of 56 patients with IgA nephropathy confirmed by renal biopsy in the Department of Renal Diseases, affiliated Hospital of Qinghai University were collected retrospectively. (2012.05-2016.10). To study the clinical and pathological characteristics of neutrophil lymphocyte ratio (NLR) and IgA nephropathy (IgA nephropathy). Results among 56 patients with IgA nephropathy, 41 were male and 15 were female. The ratio of male to female was 2.7: 1. The age was 34 鹵11 years old. Lee grade 鈪，

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