發(fā)布時間：2018-01-19 21:17

  本文關(guān)鍵詞： 新疆 地區(qū) 巴雷 食管 病理 分型 分析　出處：《新疆醫(yī)科大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:研究新疆地區(qū)人群中巴雷特食管(Barrett's esophagus BE)的病理類型、內(nèi)鏡分型、臨床癥狀的關(guān)系,及維漢兩族人群是否存在差異。方法:對604例行電子內(nèi)鏡檢查并行活組織檢查確診為BE的維漢患者進行病理類型、內(nèi)鏡分型、臨床癥狀之間的關(guān)系進行相關(guān)分析,并對維吾爾族及漢族人群中BE進行比較。結(jié)果:(1)BE總檢出率為1.29%,男:女為1.21:1,平均發(fā)病年齡為(50.84±10.89)歲。(2)BE病理分型中以賁門型(44%)、胃底型(48%)多見,三種病理類型的平均發(fā)病年齡(P0.05)、平均BMI值(P0.05)比較差異有統(tǒng)計學(xué)意義。BE內(nèi)鏡分型中以短節(jié)段巴雷特食管(Short segmental Barrett's esophagus SSBE)為主占78.64%,島型多見占73.04%。BE患者中有癥狀者占66.06%,常見的臨床癥狀為反酸、燒心、上腹不適、胸骨后不適等。幽門螺桿菌(Helicobacter pylori Hp)陽性率為29.80%。(3)維吾爾族BE檢出率1.04%,漢族BE檢出率1.46%。病理類型:維漢兩族均以賁門型、胃底型多見,腸型少見,但維漢兩族人群的賁門型、腸化型分布的構(gòu)成比較差異有統(tǒng)計學(xué)意義。兩族中內(nèi)鏡下均以SSBE為主,島型多見。維漢兩族在年齡、BMI值、食管炎等比較差異具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:新疆地區(qū)BE總的檢出率及各自的檢出率與國內(nèi)各地區(qū)BE檢出率相接近,BE三種病理類型中以賁門型及胃底型為主,其平均發(fā)病年齡明顯提前,且賁門型BMI值偏大。維吾爾族的發(fā)病年齡較漢族提前,BMI及食管炎的發(fā)生率較漢族大,維漢兩族人群賁門型及腸化型BE分布的構(gòu)成不同。因此新疆地區(qū)中年、BMI值偏大的人群應(yīng)定期行內(nèi)鏡下監(jiān)測,尤其是維吾爾族人群。
[Abstract]:Objective: to study the pathological types, endoscopic classification and clinical symptoms of Barrett's esophagus in Barrett's esophagus in Xinjiang. Methods: 604 Uygur Han patients who were diagnosed as be by electronic endoscopy and biopsy were divided into pathological type and endoscope type. The relationship between clinical symptoms was analyzed and be in Uygur and Han population was compared. Results the total detection rate of be was 1.29% for male: female 1.21: 1. The average age of onset was 50.84 鹵10.89 years old. In the pathological classification of cardia type, cardia type and stomach fundus type were more common. The mean age of onset of the three pathological types was P 0.05). The difference of mean BMI value (P 0.05) was statistically significant. In the endoscopic typing of be, the short segment of Barrett's esophagus (. Short segmental Barrett's esophagus SSBE accounted for 78.64%. Island type accounted for 73.04.be patients with symptoms accounted for 66.06, common clinical symptoms for acid reflux, heartburn, upper abdomen discomfort. Helicobacter pylori pylori positive rate of Helicobacter pylori was 29.80%. The detection rate of be in Uygur nationality was 1.04%. The detection rate of be in Han nationality was 1.46. Pathological type: both Uygur and Han nationalities had cardia type, gastric fundus type was more common, intestinal type was rare, but Uygur and Han nationality population had cardia type. The distribution of intestinal metaplasia was significantly different between the two groups under endoscopy, and the island type was more common. Uygur and Han nationality in age and SSBE value. The difference of esophagitis was statistically significant (P 0.05). Conclusion: the total detection rate of be and its detection rate in Xinjiang are close to those in China. Among the three types of be, cardia type and gastric fundus type were the main pathological types. The average onset age of be was significantly earlier than that of the Han nationality, and the BMI value of the gastric cardia type was higher. The onset age of Uygur nationality was earlier than that of Han nationality. The incidence of BMI and esophagitis was higher than that of Han nationality. The distribution of be of cardia type and intestinal type was different between Uygur and Han ethnic groups. Especially the Uygur people.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R571

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本文編號：1445566