發(fā)布時(shí)間：2018-01-20 00:21

  本文關(guān)鍵詞： 幽門螺桿菌 口腔疾病 感染　出處：《大連醫(yī)科大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：研究目的:通過調(diào)查研究口腔科住院患者對幽門螺桿菌的認(rèn)知情況及患者唾液內(nèi)幽門螺桿菌感染現(xiàn)狀,并對多種致感危險(xiǎn)因素進(jìn)行分析,總結(jié)口腔幽門螺桿菌同口腔科疾病的聯(lián)系要點(diǎn),為臨床預(yù)防治療提供數(shù)據(jù)支持及指導(dǎo)。研究對象及方法:選取對象為2016年7月～2016年12月間于大連醫(yī)科大學(xué)附屬第一醫(yī)院口腔頜面外科病房就診住院的患者,使用自制調(diào)查問卷,對患者幽門螺桿菌認(rèn)知情況打分并記錄結(jié)果。使用幽門螺桿菌尿素酶快速檢測試劑盒(干化學(xué)法)對患者進(jìn)行口內(nèi)唾液幽門螺桿菌檢測,記錄檢測結(jié)果;對測試患者進(jìn)行年齡,性別,確定診斷,吸煙飲酒史及既往全身慢性疾病史等相關(guān)數(shù)據(jù)統(tǒng)計(jì),使用SPSS20.0對相關(guān)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析,組間數(shù)據(jù)對比使用卡方檢驗(yàn),P0.05為有統(tǒng)計(jì)學(xué)意義。研究結(jié)果:根據(jù)幽門螺旋桿菌認(rèn)知度調(diào)查問卷調(diào)查,患者對幽門螺桿菌的認(rèn)知率整體較低,缺乏相關(guān)方面的知識(shí);在407位受檢住院患者中,唾液幽門螺桿菌感染結(jié)果為陽性的患者有312位,占總體的76.66%;男性246人,幽門螺桿菌感染率77.24%,女性患者總?cè)藬?shù)161人,感染率為75.78%,性別差異無統(tǒng)計(jì)學(xué)意義(P0.05);不同年齡組幽門螺桿菌感染率,隨年齡增長先上升后下降,30歲至50歲的中青年人群感染率升高,30歲以下及70歲以上患者感染率下降;不同口腔頜面外科疾病種類的患者H.pylori感染率,各組間相比,差異沒有統(tǒng)計(jì)學(xué)意義(P0.05),其中口腔頜面部感染性疾病患者34人,感染率為79.41%,其次為口腔頜面部腫瘤患者146人,感染率為78.77%;慢性疾病患者的幽門螺桿菌感染率較高,54位高血壓患者感染率83.33%,11位糖尿病患者陽性率為100%,13位同時(shí)罹患兩種慢性病患者的感染率為92.31%,329位無上述兩種慢性病患者的陽性率為74.16%,前三組感染率與最后一組分別比較,差異有統(tǒng)計(jì)學(xué)意義;受測人群中,吸煙者有144人,感染率90.97%,22位有飲酒患史者感染率為86.36%,同時(shí)有吸煙史及飲酒史的患者感染率最高,為96.08%,無吸煙史及飲酒史患者的感染率為59.47%,吸煙組、飲酒組、吸煙及飲酒組感染率分別與之相比,差異均具有統(tǒng)計(jì)學(xué)意義(P0.05)。研究結(jié)論:1.調(diào)查結(jié)果表明住院患者對幽門螺桿菌認(rèn)知度較低,大部分患者不了解幽門螺桿菌的危害性以及是導(dǎo)致多種全身系統(tǒng)疾病的致病菌之一;應(yīng)加強(qiáng)三級(jí)預(yù)防工作,做好相關(guān)知識(shí)普及,尤其是對口腔致病菌的危害性的宣教。2.本院口腔科住院患者幽門螺桿菌感染率76.66%,高于國內(nèi)現(xiàn)有報(bào)道的健康人群感染率(30～60%)。針對口腔科患者的H.pylori檢測很有必要,H.pylori的檢出率可指示某些口腔相關(guān)疾病的存在。中青年為幽門螺桿菌感染高發(fā)人群,高血壓、糖尿病及吸煙飲酒史與感染率高低正相關(guān)。3.幽門螺桿菌在口腔疾病中的作用及其與引起胃腸道疾病的機(jī)制相互間的關(guān)系,口腔幽門螺桿菌感染后的治療條件、最佳治療方案及檢測手段仍需更多的理論研究探索,望成為今后研究重點(diǎn)。
[Abstract]:Objective: through the investigation and study status quo of Department of Stomatology patients with Helicobacter pylori infection of Helicobacter pylori in saliva of patients with cognition and hospitalization, and several induced risk factors were analyzed, summed up the contact points of oral Helicobacter pylori with diseases in Department of Stomatology, to provide data support and guide the treatment for clinical prevention. Subjects and methods: the selected object for the July 2016 to December 2016 in the First Affiliated Hospital of Dalian Medical University Department of oral and maxillofacial surgery ward treatment of hospitalized patients, using self-made questionnaire on Helicobacter pylori in patients with cognitive score and record the results. The rapid detection kit of Helicobacter pylori urease (dry chemical method) of patients were detected in saliva of Helicobacter pylori, recording the detection results of the test; age, gender, diagnosis and the smoking and drinking history and past history of chronic disease such as systemic Relevant statistical data, using SPSS20.0 statistical analysis of related data, data comparison between groups using chi square test, P0.05 had statistical significance. Results: according to H.pylori cognition questionnaire investigation on cognition in Helicobacter pylori infection rate is low, the lack of relevant knowledge; in 407 subjects in hospital in patients with Helicobacter pylori infection in saliva of patients with positive results for 312, accounted for 76.66% of the total; 246 men, 77.24% rate of Helicobacter pylori infection, the total number of 161 female patients, the infection rate was 75.78%, there was no significant difference (P0.05); different age groups of Helicobacter pylori infection rate. The first increased and then decreased with the increase of age 30 to 50 years old young people increased infection rate, rate of decline under the age of 30 and 70 years of age of infection in patients with oral and maxillofacial diseases; different types of patients and the infection rate of H.pylori, Between groups were compared, the difference was not statistically significant (P0.05), including oral and maxillofacial infections in 34 patients, the infection rate was 79.41%, followed by patients with oral and maxillofacial tumor 146, the infection rate was 78.77%; a higher rate of Helicobacter pylori infection in patients with chronic diseases, 54 patients with hypertension infection rate was 83.33%. 11 in diabetic patients the positive rate was 100%, 13 and two suffering from chronic disease infection rate was 92.31%, 329 of the two kinds of chronic diseases in patients with positive rate of 74.16%, the three groups were compared with the infection rate of the last group, the difference was statistically significant; measured by the crowd, there are 144 smokers people, the infection rate was 90.97%, the infection rate of 22 patients with alcohol history was 86.36%, while the highest rate of patients with history of smoking and drinking history of infection was 96.08%, smoking and drinking history of patients with the infection rate was 59.47%, the smoking group, smoking and alcohol drinking group, infection group Rates were compared, the differences were statistically significant (P0.05). Conclusion: the survey results show that 1. of hospitalized patients on Helicobacter pylori awareness is low, most patients do not understand the harm of Helicobacter pylori and pathogen causing many systemic diseases is one of the primary prevention should be strengthened; three, good the popularization of knowledge, especially for the harm of oral pathogens in our hospital department of stomatology hospital mission.2. patients with Helicobacter pylori infection rate of 76.66%, higher than the healthy population of domestic existing reported infection rate (30 ~ 60%). It is necessary for the detection of H.pylori Department of Stomatology patients, the detection rate can indicate some oral diseases related to the presence of H.pylori the youth. In high-risk population, Helicobacter pylori infection, hypertension, diabetes and smoking and drinking history and the infection rate level is positively related to the.3. of Helicobacter pylori in oral diseases and for The relationship between the mechanism of gastrointestinal diseases and the treatment conditions of oral Helicobacter pylori infection, the best treatment and detection methods still need more theoretical research and exploration.

【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R78
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本文編號(hào)：1446095