СCLT-003{wֳٰuwƵęC(j)о
l(f)rg2024-09-21 20:07
ٰPancreatic ductal adenocarcinoma,PDAC緶(ni)yĐ[,ÿг^35f˱_\,^34f@N,5ʲ8%,С֮ķQ̖c[^,PDACһND(zhun)Ɲܵĸu[,ҌڷŻԼί,g(sh)ίЧίֶԭ,cٰW(xu)ОP(gun),߀cSg|(zh)M߶ȷѪ[h(hun)P(gun)[MȱPDACһ,cA(y)P(gun)헻A(ch)оl(f)F(xin),T(do)HIF-1߱_(d)ԴM(jn)(x)ֳֿƤ-g|(zh)D(zhun)EMTuԺD(zhun),ԼŻĵֿ҂ǰڵĶоҲCHIF-1߱_(d)ԴM(jn)ٰ(x)ֳ͵ֿ,߀ܴM(jn)ٰuw,ᘌHIF-1ܵƄڿ[ĻA(ch)RǰоеõV_չn}M@ٰķh(hun)о,СCLT-003{w҂ĺλWRꐵʿҺϳɵı...
퓔(sh)122
W(xu)λeʿ
Ŀ䛡
ժҪ
Abstract
sZ/̖f
ǰ
оF(xin)ɹ
оĿ
о
һСCLT-003{wĺϳ·ͺYx
1.1 ͷ
1.1.1 ԇ
1.1.2 ϳɷ^
1.2 Y(ji)
1.2.1 CLT-003ʽͷӽY(ji)(gu)
1.2.2 CLT-003Ҫ
1.3 ӑՓ
1.4 СY(ji)
CLT-003ٰ(x)ֳuw
2.1 ͷ
2.1.1 (x)ϵ
2.1.2 Ҫԇ
2.1.3 ƌԇ
2.1.4 ƌԇ
2.1.5 Western-BlotzƷ
2.1.6 ҪxO(sh)
2.1.7
2.1.8 y(tng)Ӌ
2.2 Y(ji)
2.2.1 CLT-003ƶN[(x)ļ(x)
2.2.2 CLT-003T(do)ٰ(x)G2/M
2.2.3 CLT-003M(jn)ٰ(x)
2.2.4 CLT-003ٰ(x)ֳ
2.2.5 CLT-003ٰ(x)uw
2.3 ӑՓ
2.4 СY(ji)
CLT-003w(ni)ٰ[L
3.1 ͷ
3.1.1 ģ
3.1.2 Ҫ(x)ϵ
3.1.3 Ҫԇ
3.1.4 P(gun)ԇ
3.1.5 ҪxO(sh)
3.1.6
3.2 Y(ji)
3.2.1 CLT-003܉ٰƤֲL
3.2.2 CLT-003ٰԭλֲL
3.3 ӑՓ
3.4 СY(ji)
CLT-003ƷT(do)HIF-1D(zhun)䛹
4.1 ͷ
4.1.1 Ҫ(x)ϵ
4.1.2 Ҫԇ
4.1.3 Ҫԇ
4.1.4 ҪxO(sh)
4.1.5 Ҫ
4.1.6 y(tng)Ӌ
4.2 Y(ji)
4.2.1 CLT-003HIF-1ΰл
4.2.2 CLT-003ӰHIF-1mRNAı_(d)ˮƽ
4.2.3 ͷlCLT-003HIF-1ױ_(d)ˮƽá
4.2.4 ͷlCLT-003HIF-1D(zhun)䛻
4.2.5 CLT-003ڄMˮƽHIF-1ױ_(d)
4.3 ӑՓ
4.4 СY(ji)
CLT-003ƷT(do)HIF-1ęC(j)о
5.1
5.1.1 Ҫļ(x)ϵ
5.1.2 Ҫԇ
5.1.3 Ҫԇ
5.1.4 ҪxO(sh)
5.1.5 Ҫ
5.1.6 y(tng)Ӌ
5.2 Y(ji)
5.2.1 CLT-003PI3K/AKT/mTOR̖ͨ·,M(jn)ӰHIF-1g^
5.2.2 CLT-003ӰHIF-1ػ^
5.2.3 CLT-003HIF-1(x){c(x)˷ֲӰ
5.3 ӑՓ
5.4 СY(ji)
ȫĽY(ji)Փ
ՓĄ(chung)c(din)
īI(xin)
l(f)Փĺͅӿrf
C ٰķh(hun)HIF-1Ƅđ(yng)ìF(xin)
CīI(xin)
x
˺v
ľ̖4006051
퓔(sh)122
W(xu)λeʿ
Ŀ䛡
ժҪ
Abstract
sZ/̖f
ǰ
оF(xin)ɹ
оĿ
о
һСCLT-003{wĺϳ·ͺYx
1.1 ͷ
1.1.1 ԇ
1.1.2 ϳɷ^
1.2 Y(ji)
1.2.1 CLT-003ʽͷӽY(ji)(gu)
1.2.2 CLT-003Ҫ
1.3 ӑՓ
1.4 СY(ji)
CLT-003ٰ(x)ֳuw
2.1 ͷ
2.1.1 (x)ϵ
2.1.2 Ҫԇ
2.1.3 ƌԇ
2.1.4 ƌԇ
2.1.5 Western-BlotzƷ
2.1.6 ҪxO(sh)
2.1.7
2.1.8 y(tng)Ӌ
2.2 Y(ji)
2.2.1 CLT-003ƶN[(x)ļ(x)
2.2.2 CLT-003T(do)ٰ(x)G2/M
2.2.3 CLT-003M(jn)ٰ(x)
2.2.4 CLT-003ٰ(x)ֳ
2.2.5 CLT-003ٰ(x)uw
2.3 ӑՓ
2.4 СY(ji)
CLT-003w(ni)ٰ[L
3.1 ͷ
3.1.1 ģ
3.1.2 Ҫ(x)ϵ
3.1.3 Ҫԇ
3.1.4 P(gun)ԇ
3.1.5 ҪxO(sh)
3.1.6
3.2 Y(ji)
3.2.1 CLT-003܉ٰƤֲL
3.2.2 CLT-003ٰԭλֲL
3.3 ӑՓ
3.4 СY(ji)
CLT-003ƷT(do)HIF-1D(zhun)䛹
4.1 ͷ
4.1.1 Ҫ(x)ϵ
4.1.2 Ҫԇ
4.1.3 Ҫԇ
4.1.4 ҪxO(sh)
4.1.5 Ҫ
4.1.6 y(tng)Ӌ
4.2 Y(ji)
4.2.1 CLT-003HIF-1ΰл
4.2.2 CLT-003ӰHIF-1mRNAı_(d)ˮƽ
4.2.3 ͷlCLT-003HIF-1ױ_(d)ˮƽá
4.2.4 ͷlCLT-003HIF-1D(zhun)䛻
4.2.5 CLT-003ڄMˮƽHIF-1ױ_(d)
4.3 ӑՓ
4.4 СY(ji)
CLT-003ƷT(do)HIF-1ęC(j)о
5.1
5.1.1 Ҫļ(x)ϵ
5.1.2 Ҫԇ
5.1.3 Ҫԇ
5.1.4 ҪxO(sh)
5.1.5 Ҫ
5.1.6 y(tng)Ӌ
5.2 Y(ji)
5.2.1 CLT-003PI3K/AKT/mTOR̖ͨ·,M(jn)ӰHIF-1g^
5.2.2 CLT-003ӰHIF-1ػ^
5.2.3 CLT-003HIF-1(x){c(x)˷ֲӰ
5.3 ӑՓ
5.4 СY(ji)
ȫĽY(ji)Փ
ՓĄ(chung)c(din)
īI(xin)
l(f)Փĺͅӿrf
C ٰķh(hun)HIF-1Ƅđ(yng)ìF(xin)
CīI(xin)
x
˺v
ľ̖4006051
朽ӣhttp://www.wukwdryxk.cn/shoufeilunwen/yxlbs/4006051.html