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СCLT-003{wֳٰuwƵęC(j)о

l(f)rg2024-09-21 20:07
ٰPancreatic ductal adenocarcinoma,PDAC緶(ni)yĐ[,ÿг^35f˱_\,^34f@N,5ʲ8%,С֮ķQ̖c[^,PDACһND(zhun)Ɲܵĸu[,ҌڷŻԼί,g(sh)ίЧίֶԭ,cٰW(xu)ОP(gun),߀cSg|(zh)M߶ȷѪ[΢h(hun)P(gun)[MȱPDACһ,cA(y)P(gun)헻A(ch)оl(f)F(xin),T(do)HIF-1߱_(d)ԴM(jn)(x)ֳֿƤ-g|(zh)D(zhun)EMTuԺD(zhun),ԼŻĵֿ҂ǰڵĶоҲCHIF-1߱_(d)ԴM(jn)ٰ(x)ֳ͵ֿ,߀ܴM(jn)ٰuw,ᘌHIF-1ܵƄڿ[ĻA(ch)RǰоеõV_չn}M@ٰķ΢h(hun)о,СCLT-003{w҂ĺλWRꐵʿҺϳɵı...

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Ŀ䛡
ժҪ
Abstract
sZ/̖f
ǰ
    оF(xin)ɹ
    оĿ
    о
һСCLT-003{wĺϳ·ͺYx
    1.1 ͷ
        1.1.1 ԇ
        1.1.2 ϳɷ^
    1.2 Y(ji)
        1.2.1 CLT-003ʽͷӽY(ji)(gu)
        1.2.2 CLT-003Ҫ
    1.3 ӑՓ
    1.4 СY(ji)
CLT-003ٰ(x)ֳuw
    2.1 ͷ
        2.1.1 (x)ϵ
        2.1.2 Ҫԇ
        2.1.3 ƌԇ
        2.1.4 ƌԇ
        2.1.5 Western-BlotzƷ
        2.1.6 ҪxO(sh)
        2.1.7 򞷽
        2.1.8 y(tng)Ӌ
    2.2 Y(ji)
        2.2.1 CLT-003ƶN[(x)ļ(x)
        2.2.2 CLT-003T(do)ٰ(x)G2/M
        2.2.3 CLT-003M(jn)ٰ(x)
        2.2.4 CLT-003ٰ(x)ֳ
        2.2.5 CLT-003ٰ(x)uw
    2.3 ӑՓ
    2.4 СY(ji)
CLT-003w(ni)ٰ[L
    3.1 ͷ
        3.1.1 ģ
        3.1.2 Ҫ(x)ϵ
        3.1.3 Ҫԇ
        3.1.4 P(gun)ԇ
        3.1.5 ҪxO(sh)
        3.1.6 򞷽
    3.2 Y(ji)
        3.2.1 CLT-003܉ٰƤֲL
        3.2.2 CLT-003ٰԭλֲL
    3.3 ӑՓ
    3.4 СY(ji)
CLT-003ƷT(do)HIF-1D(zhun)䛹
    4.1 򞌦ͷ
        4.1.1 Ҫ(x)ϵ
        4.1.2 Ҫԇ
        4.1.3 Ҫԇ
        4.1.4 ҪxO(sh)
        4.1.5 Ҫ򞷽
        4.1.6 y(tng)Ӌ
    4.2 Y(ji)
        4.2.1 CLT-003HIF-1ΰл
        4.2.2 CLT-003ӰHIF-1mRNAı_(d)ˮƽ
        4.2.3 ͷlCLT-003HIF-1ױ_(d)ˮƽá
        4.2.4 ͷlCLT-003HIF-1D(zhun)䛻
        4.2.5 CLT-003ڄMˮƽHIF-1ױ_(d)
    4.3 ӑՓ
    4.4 СY(ji)
CLT-003ƷT(do)HIF-1ęC(j)о
    5.1 󼰷
        5.1.1 Ҫļ(x)ϵ
        5.1.2 Ҫԇ
        5.1.3 Ҫԇ
        5.1.4 ҪxO(sh)
        5.1.5 Ҫ򞷽
        5.1.6 y(tng)Ӌ
    5.2 Y(ji)
        5.2.1 CLT-003PI3K/AKT/mTOR̖ͨ·,M(jn)ӰHIF-1׷g^
        5.2.2 CLT-003ӰHIF-1׷ػ^
        5.2.3 CLT-003HIF-1׼(x){c(x)˷ֲӰ
    5.3 ӑՓ
    5.4 СY(ji)
ȫĽY(ji)Փ
ՓĄ(chung)c(din)
īI(xin)
l(f)Փĺͅӿrf
C ٰķ΢h(hun)HIF-1Ƅđ(yng)ìF(xin)
    CīI(xin)
x
˺v



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