a国产,中文字幕久久波多野结衣AV,欧美粗大猛烈老熟妇,女人av天堂

珠江三角洲地區(qū)性癌癥生態(tài)地球化學(xué)研究

發(fā)布時間:2018-01-05 22:00

  本文關(guān)鍵詞:珠江三角洲地區(qū)性癌癥生態(tài)地球化學(xué)研究 出處:《中國地質(zhì)大學(xué)(北京)》2017年博士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 地區(qū)性癌癥 珠江三角洲 廣西扶綏 N-亞硝胺 地球化學(xué)致癌因子


【摘要】:醫(yī)學(xué)界認(rèn)為,目前全球性癌癥高發(fā),80-90%與環(huán)境及職業(yè)接觸有關(guān)。國際癌癥研究機構(gòu)IARC指出“癌癥發(fā)病和死亡率的地域性特征明顯”。因此研究環(huán)境因素與癌癥之間的關(guān)系對防治癌癥有重大的意義。本文選取珠江三角洲地區(qū)肝癌和鼻咽癌發(fā)病率較高的區(qū)域作為研究區(qū),本區(qū)域多年來環(huán)境因素的對癌癥的影響作用頗受關(guān)注。本文在1:5萬土壤生態(tài)地球化學(xué)詳查的基礎(chǔ)上,分別從土壤中重金屬異常、環(huán)境水與飲用水中氨氮特征、亞硝胺的含量等方面分析了研究區(qū)內(nèi)地球化學(xué)致癌因子的人為源和自然源,以及地球化學(xué)致癌因子行為的影響因素,最后通過與研究區(qū)內(nèi)癌癥發(fā)病率分布情況相結(jié)合,追蹤研究區(qū)癌癥高發(fā)的主要地球化學(xué)致癌因子。論文取得以下主要成果:1)首次在順德、四會、中山、佛山等珠江三角洲地區(qū)癌癥高發(fā)區(qū)的環(huán)境水和飲水中發(fā)現(xiàn)普遍存在的直接致癌物質(zhì)N-亞硝胺化合物。順德測區(qū)水體中亞硝胺的含量最高。15件水樣中總N-亞硝胺化合物平均含量為62.9ng/L;其中亞硝基二甲胺(NDMA)平均含量為35.1ng/L,超過國際參考飲水衛(wèi)生標(biāo)準(zhǔn)(10ng/L)3.5倍。2)NDMA為珠三角地區(qū)水體中普遍存在的且含量較高的亞硝胺化合物。其在自來水中含量水平較穩(wěn)定為22~30ng/L,認(rèn)為與生產(chǎn)過程加入的含氯消毒劑有關(guān)。在自然水體中含量水平差異較大,范圍為2.1~114.0ng/L。3)順德測區(qū)地下高銨-胺涌水與人為污染疊加,致N-亞硝胺化合物含量最高,中山、佛山情況類似,顯示高銨-污染型亞硝胺組合特征;四會測區(qū)工業(yè)發(fā)展程度相對較低,亞硝胺組合顯示為地下水原生型亞硝胺組合特征。4)廣西扶綏與珠江三角洲比較,有相似的亞硝胺形成自然條件,但是水體總體污染程度較輕,N-亞硝胺化合物含量較低,其組合接近于地下水原生型亞硝胺組合。5)順德地區(qū)土壤中重金屬元素呈強異常富集,形成三個強異常富集區(qū),其富集受到人為污染源和自然源共同影響;其他測區(qū)土壤中重金屬也有不同程度的富集異常。6)研究區(qū)內(nèi)重金屬元素在水土系統(tǒng)中的異常與癌癥空間分布沒有明顯關(guān)聯(lián);高銨地下水中NH4+、NO2-、NO3-濃度高,為N-亞硝胺的前體物,造成環(huán)境及飲用水中直接致癌物質(zhì)N-亞硝胺化合物的高含量,被認(rèn)為是研究區(qū)內(nèi)癌癥高發(fā)的主要地球化學(xué)致癌因子。
[Abstract]:The medical profession believes that the current global high incidence of cancer, 80-90% exposure and the environment and occupation. The international agency for research on cancer IARC pointed out that "regional characteristics of cancer incidence and mortality significantly. Therefore research on the relationship between environmental factors and cancer is of great significance to the prevention and treatment of cancer. This paper selects the Pearl River Delta region and the incidence of hepatocellular carcinoma in nasopharyngeal carcinoma high as the study area, the effect on cancer effect the region for many years the environmental factors of popular attention. Based on the 1:5 000 Soil Eco geochemical survey, respectively, from the soil heavy metal anomaly, environmental water and drinking water ammonia characteristics, analyzed the anthropogenic and natural sources in the area of earth chemical carcinogenesis the factor of nitrosamine content, and the influence of the earth chemical carcinogen behavior factors, the incidence of cancer in the study area and distribution With the main geochemical tracing on the area of high incidence of cancer carcinogen. The main conclusions are as follows: 1) for the first time in Shunde, Sihui, Zhongshan, Foshan and other areas in the Pearl River Delta region cancer environment and drinking water found in the direct carcinogenic N- nitrosamine compounds widely exist. The average content of the highest content of.15 water measurement in Shunde water nitrosamines in total N- nitrosamine is 62.9ng/L; the nitroso two methylamine (NDMA) the average content of 35.1ng/L, exceeding the international hygienic standard reference water (10ng/L).2 NDMA) 3.5 times for widespread water in the Pearl River Delta region and the high content of nitrosamine compounds. In the tap water level is stable for 22~30ng/L, associated with chlorine disinfectant production process. The content of adding level differences in natural water, the range of 2.1~114.0ng/L.3) measurement in Shunde underground High ammonium amine inflow and anthropogenic pollution caused by N- overlay, nitrosamine content was the highest in Zhongshan, like the Foshan show amine combination features high ammonium nitrite pollution - type test; Sihui District industrial development level is relatively low, nitrosamine combination showed groundwater native nitrosamines were characteristic of.4) compared with the Pearl River Delta of Guangxi Fusui, a natural condition for the formation of nitrosamines is similar, but the general water pollution to a lesser extent, N- nitrosamine content is low, the combination is close to the original groundwater nitrosamines combination.5) heavy metal elements in soil in Shunde region showed strong enrichment, the formation of three strong the enrichment zone, the enrichment is influenced by anthropogenic sources and natural sources; other area of heavy metals in soil have different degrees of abnormal enrichment of.6) in the research area of heavy metals in soil system abnormalities and cancer have no obvious spatial distribution Correlation; NH4+, NO2- and NO3- concentrations in high ammonium groundwater are high, and N- nitrosamines are precursors, resulting in high content of N- nitrosamines in environment and drinking water. They are considered as the main geochemical carcinogens in the study area.

【學(xué)位授予單位】:中國地質(zhì)大學(xué)(北京)
【學(xué)位級別】:博士
【學(xué)位授予年份】:2017
【分類號】:R730.2;X142

【相似文獻】

相關(guān)期刊論文 前5條

1 李銘新;致癌亞硝胺化合物的分析與合成研究的進展(文獻綜述)[J];國外醫(yī)學(xué)參考資料(腫瘤學(xué)分冊);1976年01期

2 趙華玲;煙草中特有的亞硝胺化合物[J];煙草科技;1998年03期

3 ;醬油·豆腐·醬菜[J];上海調(diào)味品;1982年02期

4 信維平;亞硝胺化合物的致癌性及防治[J];肉品衛(wèi)生;1997年02期

5 趙宇翔;王翔;胡耀銘;;GC-LRMS法測定啤酒中3種N-亞硝胺化合物[J];分析試驗室;2011年05期

相關(guān)會議論文 前2條

1 舒青;魏亞寧;吳強強;張素珍;;亞硝胺化合物致癌機理新探索[A];中國生理學(xué)會2007年消化內(nèi)分泌生殖學(xué)術(shù)研討會論文摘要匯編[C];2007年

2 阿不都卡德爾·阿不都克尤木;阿力木江·米吉提;木合塔爾·吐爾洪;;溶膠-凝膠傳感膜檢測水中的亞硝酸鹽[A];第十屆中國化學(xué)會分析化學(xué)年會暨第十屆全國原子光譜學(xué)術(shù)會議論文摘要集[C];2009年

相關(guān)博士學(xué)位論文 前1條

1 劉秀麗;珠江三角洲地區(qū)性癌癥生態(tài)地球化學(xué)研究[D];中國地質(zhì)大學(xué)(北京);2017年

,

本文編號:1384994

資料下載
論文發(fā)表

本文鏈接:http://www.wukwdryxk.cn/shoufeilunwen/yxlbs/1384994.html


Copyright(c)文論論文網(wǎng)All Rights Reserved | 網(wǎng)站地圖 |

版權(quán)申明:資料由用戶12ff2***提供,本站僅收錄摘要或目錄,作者需要刪除請E-mail郵箱bigeng88@qq.com
久久不卡日韩AⅤ精品| 色8久久人人97超碰香蕉987| 久久一区二区三区精华液介绍| 欧美老熟妇xb水多毛多| 2012中文字幕在线中字下载| 四虎网址| 孽欲| 99热| 亚洲精品a| 天堂2| 久久亚洲精品小早川怜子| 欧美一级a一级a爰片免费免免| 超碰97在线视频| 成人av动漫| 久久观看| 久久久久久久女国产乱让韩| 亚洲av无码av在线播放| 欧美黑人粗大猛烈18p| 国产末成年AV在线播放| 梅州市| 苗栗县| 清河县| 无码中文亚洲AV吉吉影音先锋| 国模杨依粉嫩蝴蝶150p| 国语自产偷拍精品视频偷拍图片| 青青草视频网| 亚洲avav国产av综合av| 香蕉成人啪国产精品视频| 激情偷乱人伦小说视频| 狠狠综合久久久久综合网小蛇| 影音先锋中文字幕人妻| а√新版天堂资源中文8| 牛牛在线视频| 亚洲日产中文字幕无码| 18禁超污无遮挡无码网址| 国产欧美国产综合每日更新| 亚洲中文无码AV永久伊人| 亚洲第一AV无码专区| 性玩弄新婚少妇hd| 美州a亚洲一视本频v色道| 襄城县|